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ICD-11

ICD-11 Codes
for XM51H6 - Diazolidinyl urea
Maja Muzhdeka February 3, 2026
Fact checked by: Teodor Jurukovski
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Alternative Names and Identifiers for Diazolidinyl Urea

Diazolidinyl urea is a synthetic antimicrobial preservative widely used in cosmetic and personal care formulations. In ingredient lists and regulatory documentation, it may appear under different names or identifiers.

Synonyms and identifiers
- Germall II trade name
- ICD-11 extension code XM51H6

Sources of Diazolidinyl Urea Exposure

Exposure to diazolidinyl urea most commonly occurs through direct skin contact. The substance is incorporated into products to inhibit microbial growth and extend shelf life.

As a formaldehyde releaser, diazolidinyl urea can release small amounts of formaldehyde over time, which is relevant to its sensitising potential.

Common sources of exposure
- Moisturisers, lotions, and creams
- Shampoos, conditioners, and hair styling products
- Makeup and other personal care products

Diazolidinyl Urea Overview and Clinical Relevance

Diazolidinyl urea, identified in ICD-11 by extension code XM51H6, functions as a broad spectrum antimicrobial preservative. It is effective against bacteria and fungi, helping maintain product safety during storage and use.

However, due to its ability to release formaldehyde, it is recognised as a potential skin sensitiser. In susceptible individuals, repeated exposure may lead to irritant or allergic contact dermatitis.

Identifying Skin Reactions to Diazolidinyl Urea

Skin reactions associated with diazolidinyl urea exposure typically present as contact dermatitis. Symptoms may develop after repeated use of products containing the preservative.

Possible clinical features
- Redness, itching, or burning at sites of contact
- Dryness, scaling, or eczematous changes
- Worsening with continued exposure to the offending product

Diagnosis is based on clinical assessment and review of product exposure history. Patch testing may be used to confirm allergic sensitivity to diazolidinyl urea or related formaldehyde releasing preservatives.

Managing Reactions and Product Selection

Management focuses on complete avoidance of diazolidinyl urea and other formaldehyde releasing preservatives. Patients should be advised to carefully review ingredient labels.

Symptomatic treatment aims to reduce inflammation and restore the skin barrier.

Management approaches
- Discontinuation of products containing diazolidinyl urea
- Use of fragrance free and preservative alternative formulations
- Topical corticosteroids or emollients for dermatitis symptoms

Coding and Documentation for Diazolidinyl Urea XM51H6

The ICD-11 extension code XM51H6 is used to identify diazolidinyl urea as a causative agent. Extension codes are applied alongside a primary diagnosis, such as allergic contact dermatitis or irritant contact dermatitis.

Accurate use of extension codes improves clinical clarity, supports epidemiological tracking of chemical exposures, and ensures appropriate medical documentation and billing.

Are Diazolidinyl Urea ICD codes billable

ICD-11 extension codes such as XM51H6 are not used alone for billing purposes. They are billable only when linked to a primary diagnosis code that represents the clinical condition being treated.

Clear documentation of exposure, symptoms, and confirmed diagnosis is required to justify the use of extension codes in medical records.

Frequently asked questions

What is the classification meaning of ICD-11 code XM51H6?
The specific classification meaning of ICD-11 code XM51H6, associated with Diazolidinyl urea, is not detailed in the provided search results. ICD-11 classifies diseases, disorders, and other health-related conditions.
How is Diazolidinyl urea represented within the ICD-11 system?
The provided information does not specify how Diazolidinyl urea (ICD-11 code XM51H6) is represented within the ICD-11 system. ICD-11 is designed to be comprehensive and digitally friendly for health data.
What are the documentation or coding usage guidelines for ICD-11 code XM51H6?
Specific documentation or coding usage guidelines for ICD-11 code XM51H6 are not available in the provided search results. ICD-11 aims for improved global interoperability and comparability of health data.
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