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ICD Hub / Diseases of the skin (L00–L99) / EA50.1 - Streptococcal toxin-mediated perineal erythema
ICD-11

ICD-11 Codes
for EA50.1 - Streptococcal toxin-mediated perineal erythema
Teodor Jurukovski January 1, 1970
Fact checked by: Teodor Jurukovski
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Understanding Streptococcal Toxin-Mediated Perineal Erythema (ICD-11 Code EA50.1)

Streptococcal toxin-mediated perineal erythema, identified by the ICD-11 code EA50.1, is a specific type of toxin-mediated cutaneous reaction. It is a skin condition triggered by toxins produced by streptococcal bacteria. This diagnosis falls under the broader category of toxin-mediated cutaneous reactions to distant or systemic bacterial infection.

Symptoms and Presentation of Toxin-Mediated Perineal Erythema

The primary symptom is a distinct erythema, or redness, typically appearing in the perineal region, often extending to the perianal area. This rash is frequently asymptomatic, described as salmon-like in colour, and may be followed by desquamation (skin peeling). Patients may experience mild, short-lived fever preceding the rash. Other associated signs can include flushed cheeks, cherry-red lips, and a strawberry tongue. Recurrent episodes of this perineal erythema are not uncommon.

Causes and Triggers: Streptococcal Pyrogenic Exotoxins

Streptococcal toxin-mediated perineal erythema is caused by superantigenic toxins released by *Streptococcus pyogenes* (group A streptococcus). These toxins circulate in the bloodstream and trigger an inflammatory response in the skin. The condition often follows a streptococcal infection, such as pharyngitis, or can be associated with other skin infections like impetigo or perianal dermatitis.

Diagnosis and Identification

Diagnosis is primarily based on the characteristic clinical presentation of the perineal rash and the patient's medical history. Laboratory tests may be used to confirm a preceding or concurrent streptococcal infection, often by isolating the bacteria from throat or perianal cultures. Healthcare providers differentiate this condition from other causes of perineal rashes and similar systemic reactions.

Treatment Considerations for Toxin-Mediated Perineal Erythema

Treatment typically involves systemic antimicrobial therapy to address the underlying streptococcal infection. While the condition can resolve spontaneously, medical intervention is crucial for accurate diagnosis and appropriate management. Patients experiencing symptoms suggestive of toxin-mediated perineal erythema should seek prompt medical advice.

Coding and Documentation: ICD-11 Code EA50.1

For accurate medical record-keeping and billing, the ICD-11 code EA50.1 is used. This specific code, EA50.1, officially represents Streptococcal toxin-mediated perineal erythema. Utilising the correct ICD-11 code ensures precise documentation of the patient's condition for healthcare providers and billing services. This code is essential for reporting and tracking cases of this specific toxin-mediated skin reaction.

Frequently asked questions

What is the ICD-11 classification for Streptococcal toxin-mediated perineal erythema?
The ICD-11 code for Streptococcal toxin-mediated perineal erythema is EA50.1, which falls under the broader category of Toxin-mediated cutaneous reactions to distant or systemic bacterial infection (EA50).
When should the ICD-11 code EA50.1 be used versus other codes in the EA50 block?
EA50.1 is used when the condition is specifically identified as Streptococcal toxin-mediated perineal erythema. For cases where the specific bacterium is not identified or the reaction is otherwise specified, other codes within the EA50 block, such as EA50.Y (Other specified toxin-mediated cutaneous reactions to distant or systemic bacterial infection) or EA50.Z (Toxin-mediated cutaneous reactions to distant or systemic bacterial infection, unspecified), may be applicable.
How does EA50.1 relate to other toxin-mediated cutaneous reactions in ICD-11?
EA50.1 is a specific classification for reactions mediated by streptococcal toxins affecting the perineal area. It is distinct from other conditions within the EA50 block, such as Erythema marginatum rheumaticum (EA50.0) or Staphylococcal scalded skin syndrome (EA50.2).
What is the precise ICD-11 terminology for code EA50.1?
The precise ICD-11 terminology for code EA50.1 is Streptococcal toxin-mediated perineal erythema.
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