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ICD Hub / Symptoms, signs or clinical findings, not elsewhere classified (R00–R99) / MA01.1 - Generalised lymph node enlargement
ICD-11

ICD-11 Codes
for MA01.1 - Generalised lymph node enlargement
Teodor Jurukovski January 1, 1970
Fact checked by: Teodor Jurukovski
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Understanding Generalised Lymph Node Enlargement

Generalised lymph node enlargement, also known clinically as generalised lymphadenopathy, refers to the abnormal enlargement of lymph nodes in two or more non-contiguous regions of the body. This condition, identified by the ICD-11 code MA01.1, signifies that the body's immune system is actively responding to an issue. While often associated with common infections, it can also indicate more complex underlying health concerns. Patient-friendly terms like 'swollen glands' are sometimes used, but it is important to note that lymph nodes are distinct from glands.

Recognising the Signs of Generalised Lymphadenopathy

The primary sign of generalised lymphadenopathy is the palpable enlargement of lymph nodes. Healthcare professionals assess these nodes for characteristics such as size, shape, pain or tenderness upon touch, consistency (whether they feel hard or rubbery), and whether they form clusters that feel stuck together (matting). The distribution of swelling across multiple, distinct body areas, rather than a single localized group, is a key indicator of a generalised condition.

Factors Contributing to Widespread Lymph Node Swelling

Generalised lymph node enlargement can stem from a variety of causes. Common triggers include infections, such as viral illnesses like the common cold, flu, or mononucleosis, and bacterial infections like strep throat. Less commonly, it may be associated with autoimmune diseases, reactions to certain medications, or more serious conditions including blood cancers, metastatic cancers, or sexually transmitted infections. The presence of generalised swelling often suggests a systemic process affecting multiple body systems.

Diagnostic Approaches for Generalised Lymph Node Enlargement

Diagnosing generalised lymph node enlargement involves a comprehensive evaluation by a healthcare provider. This typically begins with a detailed medical history and a thorough physical examination to assess the characteristics of the swollen lymph nodes. Further investigations may include blood tests, other laboratory analyses, and potentially a lymph node biopsy to determine the precise cause of the enlargement.

Coding and Documentation for ICD-11 MA01.1

The official ICD-11 code for Generalised lymph node enlargement is MA01.1. Common clinical synonyms include generalised lymphadenopathy. For accurate medical documentation and billing purposes, it is crucial to specify that the lymph node enlargement is generalised, meaning it affects multiple, non-contiguous areas. This distinction is vital for differentiating it from localised lymph node enlargement (MA01.0).

When to Consult a Healthcare Professional

It is advisable to seek medical attention if you experience swollen lymph nodes in multiple, non-adjacent areas of your body, especially if there is no obvious cause such as a recent infection. Consult a healthcare provider if the nodes are larger than 2 centimeters, grow rapidly, are fixed and do not move, are very painful, or if they are accompanied by systemic symptoms like unexplained weight loss, night sweats, persistent fever, difficulty breathing, or significant fatigue. Prompt evaluation is recommended for any concerning changes or persistent swelling.

Frequently asked questions

What is the ICD-11 classification meaning of Generalised lymph node enlargement (MA01.1)?
Generalised lymph node enlargement (MA01.1) denotes the abnormal enlargement of lymph nodes affecting two or more non-contiguous anatomical sites.
What are the exclusions for Generalised lymph node enlargement (MA01.1) in ICD-11?
ICD-11 excludes conditions such as Human immunodeficiency virus disease associated with generalised lymphadenopathy (1C62.0) from MA01.1.
How does ICD-11 differentiate Generalised lymph node enlargement (MA01.1) from localized enlargement?
Generalised lymph node enlargement (MA01.1) is distinguished by the involvement of lymph nodes in multiple, non-contiguous anatomical regions, as opposed to localized enlargement.
Is post-coordination applicable to Generalised lymph node enlargement (MA01.1) in ICD-11?
Yes, ICD-11 permits post-coordination with MA01.1 to specify the anatomical sites involved in the generalised lymph node enlargement using extension codes.
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